John: Created page with "
:'''Summary''' :Expressed on acute myeloid leukaemias with more mature features, particularly those with granulocytic maturation, CD11b is also expressed on monocytes (although less so than CD11c). Expression of CD11b may be used to support the identification of mixed phenotype acute leukaemia MPAL.
:'''B..."

2023-05-27T15:31:56Z

Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> :<span style="color:navy">'''Summary'''</span> :Expressed on acute myeloid leukaemias with more mature features, particularly those with granulocytic maturation, CD11b is also expressed on monocytes (although less so than CD11c). Expression of CD11b may be used to support the identification of mixed phenotype acute leukaemia MPAL. </div> :<span style="color:navy">'''B..."

New page

<div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;">

:<span style="color:navy">'''Summary'''</span>

:Expressed on acute myeloid leukaemias with more mature features, particularly those with granulocytic maturation, CD11b is also expressed on monocytes (although less so than CD11c). Expression of CD11b may be used to support the identification of mixed phenotype acute leukaemia MPAL.

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:<span style="color:navy">'''Background'''</span>

:This is a leukocyte integrin receptor expressed by myeloid cells; in contrast to the closely related CD11c, CD11b is predominantly a marker of neutrophil maturation acquired after the more primitive blast cell stage then showing stronger expression as precursor cells mature.

:<span style="color:navy">'''Diagnostic Use'''</span>

*Expression of CD11b may be used to support the identification of mixed phenotype acute leukaemia MPAL.

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CD11b - Revision history