Flow cytometry: Follicular Lymphoma - Revision history

John at 15:17, 13 July 2023

2023-07-13T15:17:35Z

← Older revision		Revision as of 17:17, 13 July 2023
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	!colspan="4" style = "font-size:90%; background:#DAE8F2"\|'''CD45''' expression		!colspan="4" style = "font-size:90%; background:#DAE8F2"\|'''CD45''' expression
	\|-		\|-
	\|colspan="4" style = "font-size:90%; color:black;" \|Typically expression of CD45 ~~is less intense than~~ normal T or B cells~~, with many cases showing variable expression with a wide spread of CD45 intensity~~.		\|colspan="4" style = "font-size:90%; color:black;" \|Typically expression of CD45 approaches that of normal T and B cells.
	\|-		\|-
	!colspan="4" style = "font-size:90%; background:#DAE8F2"\|'''Major markers useful in diagnosis'''		!colspan="4" style = "font-size:90%; background:#DAE8F2"\|'''Major markers useful in diagnosis'''

2023-07-13T15:15:23Z

← Older revision		Revision as of 17:15, 13 July 2023
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	{\| class="wikitable" style="color:black; background-color:#ffffff;" cellpadding="5"		{\| class="wikitable" style="color:black; background-color:#ffffff;" cellpadding="5"
	!colspan="4" style = "font-size:110%; color: navy; text-align:center; background:#DEE0DE;"\|'''Immunophenotype of FL'''		!colspan="4" style = "font-size:110%; color: navy; text-align:center; background:#DEE0DE;"\|'''Immunophenotype of FL'''
			\|-
			!colspan="4" style = "font-size:90%; background:#DAE8F2"\|'''CD45''' expression
			\|-
			\|colspan="4" style = "font-size:90%; color:black;" \|Typically expression of CD45 is less intense than normal T or B cells, with many cases showing variable expression with a wide spread of CD45 intensity.
	\|-		\|-
	!colspan="4" style = "font-size:90%; background:#DAE8F2"\|'''Major markers useful in diagnosis'''		!colspan="4" style = "font-size:90%; background:#DAE8F2"\|'''Major markers useful in diagnosis'''

2023-07-13T12:07:53Z

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	----		----
			<gallery mode="nolines" widths="200px" heights="200px" border="1px" >
	[[file:FL.jpg~~\|200px~~\|link=FL.jpg]]		file:FL.jpg\|link={{filepath:FL.jpg}}
			</gallery>
	~~<span style="font-size:90%">''Typical FCL morphology''~~</~~span~~>		----

2023-07-12T19:12:14Z

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	However, individual markers may not be expressed in all cases - confirmation can be made from histopathology, cytogenetic or genetic testing.		However, individual markers may not be expressed in all cases - confirmation can be made from histopathology, cytogenetic or genetic testing.


	~~'''CD45 Expression'''~~


	~~[[file:FCLCD45.jpg\|300px\|link=FCLCD45.jpg]]~~


	~~<span style="font-size:90%">''Side scatter''~~

2023-07-12T19:11:53Z

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	----		----

	[[file:~~FCL~~.jpg\|200px\|link=~~FCL~~.jpg]]		[[file:FL.jpg\|200px\|link=FL.jpg]]

	<span style="font-size:90%">''Typical FCL morphology''</span>		<span style="font-size:90%">''Typical FCL morphology''</span>

2023-07-04T20:21:19Z

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	<span style="color:navy;font-size:80% ">'''Key to table: '''</span>		<span style="color:navy;font-size:80% ">'''Key to table: '''</span>

	~~<span style="font-size:80% ">Markers most useful in initial diagnosis are <span style=color:navy><u>underlined in blue text</u></span></span>~~

	<span style="font-size:80% ">Key to colour code for expression frequency [[Key_to_marker_expression_table\|Click for link]]</span>		<span style="font-size:80% ">Key to colour code for expression frequency [[Key_to_marker_expression_table\|Click for link]]</span>

2023-07-04T20:19:06Z

← Older revision		Revision as of 22:19, 4 July 2023
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	!colspan="4" style = "font-size:110%; color: navy; text-align:center; background:#DEE0DE;"\|'''Immunophenotype of FL'''		!colspan="4" style = "font-size:110%; color: navy; text-align:center; background:#DEE0DE;"\|'''Immunophenotype of FL'''
	\|-		\|-
	!colspan="4" style = "font-size:90%; background:#DAE8F2"\|'''Major markers useful in ~~CLL~~ diagnosis'''		!colspan="4" style = "font-size:90%; background:#DAE8F2"\|'''Major markers useful in diagnosis'''
	\|-		\|-
	\|colspan="1" style = "font-size:80%; width: 4%; \|'''Marker'''		\|colspan="1" style = "font-size:80%; width: 4%; \|'''Marker'''

2023-07-04T20:18:34Z

← Older revision		Revision as of 22:18, 4 July 2023
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	\|colspan="1" style = "font-size:80%;"\|		\|colspan="1" style = "font-size:80%;"\|
	\|colspan="1" style = "font-size:84%;"\|Expression is expected and should be stronger than CLL		\|colspan="1" style = "font-size:84%;"\|Expression is expected and should be stronger than CLL
			\|-
			\|colspan="1" style = "font-size:90%; color:black;" \|CD200
			\|colspan="1" style = "background:#E6FAFF;"\|
			\|colspan="1" style = "font-size:80%;"\|-
			\|colspan="1" style = "font-size:84%;"\|Characteristically (though not always) negative in FL
	\|-		\|-
	\|colspan="1" style = "font-size:90%; color:black;" \|FMC7		\|colspan="1" style = "font-size:90%; color:black;" \|FMC7
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	\|colspan="1" style = "font-size:80%;"\|-		\|colspan="1" style = "font-size:80%;"\|-
	\|colspan="1" style = "font-size:84%;"\|Predominantly expressed at plasma cell differentiation		\|colspan="1" style = "font-size:84%;"\|Predominantly expressed at plasma cell differentiation
	\|-
	~~\|colspan="1" style = "font-size:90%; color:black;" \|CD200~~
	~~\|colspan="1" style = "background:#E6FAFF;"\|~~
	~~\|colspan="1" style = "font-size:80%;"\|-~~
	~~\|colspan="1" style = "font-size:84%;"\|Characteristically (though not always) negative in FL~~
	\|-		\|-
	\|}		\|}

2023-07-04T20:17:23Z

← Older revision		Revision as of 22:17, 4 July 2023
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	\|colspan="1" style = "font-size:80%;"\|-		\|colspan="1" style = "font-size:80%;"\|-
	\|colspan="1" style = "font-size:84%;"\|May be expressed by some cases of FL		\|colspan="1" style = "font-size:84%;"\|May be expressed by some cases of FL
			\|-
			\|colspan="1" style = "font-size:90%; color:black;" \|CD79b
			\|colspan="1" style = "background:#004466;"\|
			\|colspan="1" style = "font-size:80%;"\|
			\|colspan="1" style = "font-size:84%;"\|Expression is expected and should be stronger than CLL
	\|-		\|-
	\|colspan="1" style = "font-size:90%; color:black;" \|FMC7		\|colspan="1" style = "font-size:90%; color:black;" \|FMC7
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	\|colspan="1" style = "font-size:80%;"\|-		\|colspan="1" style = "font-size:80%;"\|-
	\|colspan="1" style = "font-size:84%;"\|Expression is uncommon in FL, may be helpful in some cases		\|colspan="1" style = "font-size:84%;"\|Expression is uncommon in FL, may be helpful in some cases
	\|-
	~~\|colspan="1" style = "font-size:90%; color:black;" \|CD79b~~
	~~\|colspan="1" style = "background:#004466;"\|~~
	~~\|colspan="1" style = "font-size:80%;"\|~~
	~~\|colspan="1" style = "font-size:84%;"\|Expression is expected and should be stronger than CLL~~
	\|-		\|-
	\|colspan="1" style = "font-size:90%;" \|CD103		\|colspan="1" style = "font-size:90%;" \|CD103

2023-07-04T20:16:20Z

@@ Line 44: / Line 44: @@
 |colspan="1" style = "font-size:80%;"|-
 |colspan="1" style = "font-size:84%;"|Expression is expected, but may be weak or undectable
 |-
 |colspan="1" style = "font-size:90%; color:black;" |CD5
@@ Line 59: / Line 54: @@
 |colspan="1" style = "font-size:80%;"|Strg
 |colspan="1" style = "font-size:84%;"|Expression is expected though not universal in FL
 |-
 !colspan="4" style = "font-size:90%; background:#DAE8F2"|Other relevant markers
@@ Line 71: / Line 76: @@
 |colspan="1" style = "font-size:80%;"|-
 |colspan="1" style = "font-size:84%;"|Expression is expected, rare cases may have CD20 loss
 |-
 |colspan="1" style = "font-size:90%; color:black;" |CD25