Plasmodium ovale: Morphology - Revision history

Admin at 19:25, 13 December 2024

2024-12-13T19:25:06Z

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			This early growth stage has mainly large sized ring forms, but also begins to acquire characteristic features of the species.
	*Large and robust-appearing [[rings]], not usually multiply infected		*Large and robust-appearing [[rings]], not usually multiply infected
	*Red cells may become enlarged and may be ovoid or have a [[fimbriated]] apearance		*Red cells may become enlarged and may be ovoid or have a [[fimbriated]] apearance

Admin at 12:26, 7 May 2024

2024-05-07T12:26:27Z

← Older revision		Revision as of 14:26, 7 May 2024
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	*A range of [[maturing schizonts]] will generally be present within moderately enlarged red cells		*A range of [[maturing schizonts]] will generally be present within moderately enlarged red cells
	*When mature schizonts may contain 16-24 separate [[merozoites]]		*When mature schizonts may contain 16-24 separate [[merozoites]]
	*[[~~Schüffner~~'s dots]] can be detected in any residual cytoplasm of the erythrocyte		*[[James' dots]] can be detected in any residual cytoplasm of the erythrocyte
	*[[Malaria pigment\|malaria pigment]] is visible in irregularly distributed clumps over the schizont surface		*[[Malaria pigment\|malaria pigment]] is visible in irregularly distributed clumps over the schizont surface

Admin at 12:25, 7 May 2024

2024-05-07T12:25:34Z

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	*Large and robust-appearing rings, not ~~generally~~ multiply infected		*Large and robust-appearing [[rings]], not usually multiply infected
	*Red cells may become enlarged, and may be ovoid or fimbriated apearance		*Red cells may become enlarged and may be ovoid or have a [[fimbriated]] apearance
	*James' dots (indistinguishable from Schuffner’s dots) often appear		*[[James' dots]] (indistinguishable from Schuffner’s dots) often appear
	*Pigment will not generally be present at the early trophozoite stage		*Pigment will not generally be present at the early trophozoite stage

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	*Parasites become larger and thickened, but the ring form is generally retained		*Parasites become larger and thickened, but the ring form is generally retained
	*Red cell enlargement is seen and distortion causing ovoid and fimbriated forms		*[[Red cell enlargement]] is seen and distortion causing ovoid and [[fimbriated]] forms
	*James’ dots will now be prominent in appropriately stained specimens		*[[James’ dots]] will now be prominent in appropriately stained specimens
	*Pigment will now be seen over the surface of the parasite		*[[Pigment]] will now be seen over the surface of the parasite


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	The asexual stage of [[malaria parasite development]] - only some trophozoites form schizonts, but those that do undergo successive cycles of replication within the red cell to generate multiple [["merozoites"]] that then each invade a new red cell to continue and increase the infection.		The asexual stage of [[malaria parasite development]] - only some trophozoites form schizonts, but those that do undergo successive cycles of replication within the red cell to generate multiple [["merozoites"]] that then each invade a new red cell to continue and increase the infection.

	*a range of maturing schizonts will generally be present within enlarged red cells		*A range of [[maturing schizonts]] will generally be present within moderately enlarged red cells
	*~~when~~ mature schizonts may contain 16-24 separate merozoites		*When mature schizonts may contain 16-24 separate [[merozoites]]
	*[[Schüffner's dots]] can be detected in any residual cytoplasm of the erythrocyte		*[[Schüffner's dots]] can be detected in any residual cytoplasm of the erythrocyte
	*[[Malaria pigment\|malaria pigment]] is visible in irregularly distributed clumps over the schizont surface		*[[Malaria pigment\|malaria pigment]] is visible in irregularly distributed clumps over the schizont surface
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	The sexual replication form (very distinctive).		The sexual replication form (very distinctive).

	*~~red~~ cells are very large and have ovoid or distorted forms		*Red cells are very large and have ovoid or distorted forms
	*~~macrogametocytes~~ (female form) will often entirely fill the erythrocyte		*[[Macrogametocytes]] (female form) will often entirely fill the erythrocyte
	*~~microgametocytes~~ (male form) have a cytoplasmic rim with visible Schüffner's dots		*[[Microgametocytes]] (male form) have a cytoplasmic rim with visible Schüffner's dots
	*[[Malaria pigment\|malaria pigment]] is clumped evenly over the surface of the gametocyte		*[[Malaria pigment\|malaria pigment]] is clumped evenly over the surface of the gametocyte

Admin at 18:14, 4 May 2024

2024-05-04T18:14:05Z

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	~~The later~~ growth stage ~~during which~~ parasites ~~grow considerably and lose their~~ ring ~~appearance~~, this process is accompanied by ~~substantial~~ modification of the red cell and metabolism of ~~it's~~ haemoglobin to form ~~malaria pigment~~.		During this growth stage parasites grows but generally retain a ring shape, this process is accompanied by further modification of the red cell with ovoid and fimbriated features more common; metabolism of haemoglobin causes malaria pigment to form.

	*~~infected erythrocytes~~ become ~~significantly enlarged~~ and ~~irregular in shape~~		*Parasites become larger and thickened, but the ring form is generally retained
	*~~parasites lose their ring appearnace becoming irregular~~ and ~~"[[amoeboid]]" in form~~		*Red cell enlargement is seen and distortion causing ovoid and fimbriated forms
	*~~numerous red/purple Schüffner's~~ dots ~~are predent~~ in the ~~cytoplasm~~ of ~~red cells~~		*James’ dots will now be prominent in appropriately stained specimens
	*[[malaria pigment]] is often present and has an irregular distribution		*Pigment will now be seen over the surface of the parasite

Admin at 17:56, 4 May 2024

2024-05-04T17:56:06Z

← Older revision		Revision as of 19:56, 4 May 2024
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	*Large and robust-appearing rings, not generally ~~multiple infection~~		*Large and robust-appearing rings, not generally multiply infected
	*Red cells may become enlarged, and may ~~show early~~ ovoid or fimbriated apearance		*Red cells may become enlarged, and may be ovoid or fimbriated apearance
	*James' dots (indistinguishable from Schuffner’s dots) ~~may~~ appear		*James' dots (indistinguishable from Schuffner’s dots) often appear
	*Pigment will not generally be present at the early trophozoite stage		*Pigment will not generally be present at the early trophozoite stage

Admin at 17:54, 4 May 2024

2024-05-04T17:54:50Z

← Older revision		Revision as of 19:54, 4 May 2024
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	~~The earliest ring forms may be indistinguishable from other species, but during this stage the parasite tends to aquire a more irregular forms~~ and ~~to show signs of modification of the erythrocyte (added dots~~, ~~and altered size and shape).~~		*Large and robust-appearing rings, not generally multiple infection
			*Red cells may become enlarged, and may show early ovoid or fimbriated apearance
	*~~erythrocytes begin to show increased [[~~Red ~~cell size~~ and ~~shape: P.vivax\|size and altered shape]]~~		*James' dots (indistinguishable from Schuffner’s dots) may appear
	*parasites retain a ring form but may ~~aquire a more irregular form~~		*Pigment will not generally be present at the early trophozoite stage
	*parasites are generally large - occupying up to half of the erythrocyte
	*~~cytoplasmic [[Schüffner~~'s dots]] may appear at ~~this~~ stage~~, although pigment is less uncommon~~

Admin at 08:24, 2 May 2024

2024-05-02T08:24:37Z

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	File:PVSc.jpg\|link={{filepath:PFSc.jpg}}		File:PVSc.jpg\|link={{filepath:PFSc.jpg}}
	File:~~PVO~~ main.jpg\|link={{filepath:~~PFO~~ main.jpg}}		File:POS main.jpg\|link={{filepath:POS main.jpg}}
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Admin at 08:21, 2 May 2024

2024-05-02T08:21:02Z

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	<gallery mode="nolines" widths=200px heights=200px>		<gallery mode="nolines" widths=200px heights=200px>
	File:~~PVOc~~.jpg\|link={{filepath:~~PVOc~~.jpg}}		File:POGc.jpg\|link={{filepath:POGc.jpg}}
	File:~~PVO~~ main.jpg\|link={{filepath:~~PVO~~ main.jpg}}		File:POG main.jpg\|link={{filepath:POG main.jpg}}
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Admin at 07:47, 2 May 2024

2024-05-02T07:47:14Z

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	<gallery mode="nolines" widths=200px heights=200px>		<gallery mode="nolines" widths=200px heights=200px>
	File:~~PVETc~~.jpg\|link={{filepath:~~PVETc~~.jpg}}		File:POETc.jpg\|link={{filepath:POETc.jpg}}
	File:~~PVET~~ main.jpg\|link={{filepath:~~PVET~~ main.jpg}}		File:POET main.jpg\|link={{filepath:POET main.jpg}}
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	<div style="width: 350px">		<div style="width: 350px">
	{\| class="wikitable" style="border-left:solid 4px navy;border-right:solid 4px navy;border-top:solid 4px navy;border-bottom:solid 4px navy; font-size:90%; color:navy; align:center"		{\| class="wikitable" style="border-left:solid 4px navy;border-right:solid 4px navy;border-top:solid 4px navy;border-bottom:solid 4px navy; font-size:90%; color:navy; align:center"
	\| colspan="1"''\|[[P.~~vivax~~ early trophozoites gallery\|Click for ''P.~~vivax~~'' early trophozoite gallery]]''		\| colspan="1"''\|[[P.ovale early trophozoites gallery\|Click for ''P.ovale'' early trophozoite gallery]]''
	\|}		\|}
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	<gallery mode="nolines" widths=200px heights=200px>		<gallery mode="nolines" widths=200px heights=200px>
	File:~~PVLTc~~.jpg\|link={{filepath:~~PVLTc~~.jpg}}		File:POLTc.jpg\|link={{filepath:POLTc.jpg}}
	File:~~PVLT~~ main.jpg\|link={{filepath:~~PVLT~~ main.jpg}}		File:POLT main.jpg\|link={{filepath:POLT main.jpg}}
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	{\| class="wikitable" style="border-left:solid 4px navy;border-right:solid 4px navy;border-top:solid 4px navy;border-bottom:solid 4px navy; font-size:90%; color:navy; align:center"		{\| class="wikitable" style="border-left:solid 4px navy;border-right:solid 4px navy;border-top:solid 4px navy;border-bottom:solid 4px navy; font-size:90%; color:navy; align:center"
	\| colspan="1"''\|[[P.~~vivax~~ late trophozoites gallery\|Click for ''P.~~vivax~~'' late trophozoite gallery]]''		\| colspan="1"''\|[[P.ovale late trophozoites gallery\|Click for ''P.ovale'' late trophozoite gallery]]''
	\|}		\|}
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	<gallery mode="nolines" widths=200px heights=200px>		<gallery mode="nolines" widths=200px heights=200px>
	File:PVSc.jpg\|link={{filepath:PFSc.jpg}}		File:PVSc.jpg\|link={{filepath:PFSc.jpg}}
	File:~~PVS~~ main.jpg\|link={{filepath:~~PFS~~ main.jpg}}		File:PVO main.jpg\|link={{filepath:PFO main.jpg}}
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	{\| class="wikitable" style="border-left:solid 4px navy;border-right:solid 4px navy;border-top:solid 4px navy;border-bottom:solid 4px navy; font-size:90%; color:navy; align:center"		{\| class="wikitable" style="border-left:solid 4px navy;border-right:solid 4px navy;border-top:solid 4px navy;border-bottom:solid 4px navy; font-size:90%; color:navy; align:center"
	\| colspan="1"''\|[[P.~~vivax~~ schizont gallery\|Click for ''P.~~vivax~~'' schizont gallery]]''		\| colspan="1"''\|[[P.ovale schizont gallery\|Click for ''P.ovale'' schizont gallery]]''
	\|}		\|}
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	<gallery mode="nolines" widths=200px heights=200px>		<gallery mode="nolines" widths=200px heights=200px>
	File:~~PVGc~~.jpg\|link={{filepath:~~PVGc~~.jpg}}		File:PVOc.jpg\|link={{filepath:PVOc.jpg}}
	File:~~PVG~~ main.jpg\|link={{filepath:~~PVG~~ main.jpg}}		File:PVO main.jpg\|link={{filepath:PVO main.jpg}}
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	{\| class="wikitable" style="border-left:solid 4px navy;border-right:solid 4px navy;border-top:solid 4px navy;border-bottom:solid 4px navy; font-size:90%; color:navy; align:center"		{\| class="wikitable" style="border-left:solid 4px navy;border-right:solid 4px navy;border-top:solid 4px navy;border-bottom:solid 4px navy; font-size:90%; color:navy; align:center"
	\| colspan="1"''\|[[P.~~vivax~~ gametocyte gallery\|Click for ''P.~~vivax~~'' gametocyte gallery]]''		\| colspan="1"''\|[[P.ovale gametocyte gallery\|Click for ''P.ovale'' gametocyte gallery]]''
	\|}		\|}
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Admin: Created page with "---- '''Navigation'''
(click blue highlighted text to return to page)

Malaria main index
>Species identification: summary page
>>This page: ''P.ovale'': morphology ---- {| class="wikitable" style="border-style: solid; border-width: 5px; border-color: #023020; color:black" |colspa..."

2024-05-02T07:32:25Z

Created page with "---- '''Navigation'''</br> <span style="font-size:80%">(click blue highlighted text to return to page)</span></br></br> <span style="font-size:90%">Malaria main index</span></br> <span style="font-size:90%">>Species identification: summary page</span></br> <span style="font-size:90%">>>This page: <u>''P.ovale'': morphology</u></span> ---- {| class="wikitable" style="border-style: solid; border-width: 5px; border-color: #023020; color:black" |colspa..."

New page

----
'''Navigation'''</br>
<span style="font-size:80%">(click blue highlighted text to return to page)</span></br></br>
<span style="font-size:90%">[[Malaria Index|Malaria main index]]</span></br>
<span style="font-size:90%">>[[Species identification: summary page]]</span></br>
<span style="font-size:90%">>>This page: <u>''P.ovale'': morphology</u></span>
----

{| class="wikitable" style="border-style: solid; border-width: 5px; border-color: #023020; color:black"
|colspan="1" style = "font-size:100%; color:black; background: CBD5CO |'''The early trophozoite'''
|}

<gallery mode="nolines" widths=200px heights=200px>
File:PVETc.jpg|link={{filepath:PVETc.jpg}}
File:PVET main.jpg|link={{filepath:PVET main.jpg}}
</gallery>
<br clear=all>

The earliest ring forms may be indistinguishable from other species, but during this stage the parasite tends to aquire a more irregular forms and to show signs of modification of the erythrocyte (added dots, and altered size and shape).

*erythrocytes begin to show increased [[Red cell size and shape: P.vivax|size and altered shape]]
*parasites retain a ring form but may aquire a more irregular form
*parasites are generally large - occupying up to half of the erythrocyte
*cytoplasmic [[Schüffner's dots]] may appear at this stage, although pigment is less uncommon

<div style="width: 350px">
{| class="wikitable" style="border-left:solid 4px navy;border-right:solid 4px navy;border-top:solid 4px navy;border-bottom:solid 4px navy; font-size:90%; color:navy; align:center"
| colspan="1"''|[[P.vivax early trophozoites gallery|Click for ''P.vivax'' early trophozoite gallery]]''
|}
</div>

----

{| class="wikitable" style="border-style: solid; border-width: 5px; border-color: #023020; color:black"
|colspan="1" style = "font-size:100%; color:black; background: CBD5CO |'''The late trophozoite'''
|}

<gallery mode="nolines" widths=200px heights=200px>
File:PVLTc.jpg|link={{filepath:PVLTc.jpg}}
File:PVLT main.jpg|link={{filepath:PVLT main.jpg}}
</gallery>
<br clear=all>

The later growth stage during which parasites grow considerably and lose their ring appearance, this process is accompanied by substantial modification of the red cell and metabolism of it's haemoglobin to form malaria pigment.

*infected erythrocytes become significantly enlarged and irregular in shape
*parasites lose their ring appearnace becoming irregular and "[[amoeboid]]" in form
*numerous red/purple Schüffner's dots are predent in the cytoplasm of red cells
*[[malaria pigment]] is often present and has an irregular distribution

<div style="width: 350px">
{| class="wikitable" style="border-left:solid 4px navy;border-right:solid 4px navy;border-top:solid 4px navy;border-bottom:solid 4px navy; font-size:90%; color:navy; align:center"
| colspan="1"''|[[P.vivax late trophozoites gallery|Click for ''P.vivax'' late trophozoite gallery]]''
|}
</div>

----

{| class="wikitable" style="border-style: solid; border-width: 5px; border-color: #023020; color:black"
|colspan="1" style = "font-size:100%; color:black; background: CBD5CO |'''The schizont'''
|}

<gallery mode="nolines" widths=200px heights=200px>
File:PVSc.jpg|link={{filepath:PFSc.jpg}}
File:PVS main.jpg|link={{filepath:PFS main.jpg}}
</gallery>
<br clear=all>

The asexual stage of [[malaria parasite development]] - only some trophozoites form schizonts, but those that do undergo successive cycles of replication within the red cell to generate multiple [["merozoites"]] that then each invade a new red cell to continue and increase the infection.

*a range of maturing schizonts will generally be present within enlarged red cells
*when mature schizonts may contain 16-24 separate merozoites
*[[Schüffner's dots]] can be detected in any residual cytoplasm of the erythrocyte
*[[Malaria pigment|malaria pigment]] is visible in irregularly distributed clumps over the schizont surface

<div style="width: 350px">
{| class="wikitable" style="border-left:solid 4px navy;border-right:solid 4px navy;border-top:solid 4px navy;border-bottom:solid 4px navy; font-size:90%; color:navy; align:center"
| colspan="1"''|[[P.vivax schizont gallery|Click for ''P.vivax'' schizont gallery]]''
|}
</div>

----

'''The gametocyte'''

{| class="wikitable" style="border-style: solid; border-width: 5px; border-color: #023020; color:black"
|colspan="1" style = "font-size:100%; color:black; background: CBD5CO |'''The gametocyte'''
|}

<gallery mode="nolines" widths=200px heights=200px>
File:PVGc.jpg|link={{filepath:PVGc.jpg}}
File:PVG main.jpg|link={{filepath:PVG main.jpg}}
</gallery>
<br clear=all>

The sexual replication form (very distinctive).

*red cells are very large and have ovoid or distorted forms
*macrogametocytes (female form) will often entirely fill the erythrocyte
*microgametocytes (male form) have a cytoplasmic rim with visible Schüffner's dots
*[[Malaria pigment|malaria pigment]] is clumped evenly over the surface of the gametocyte

<div style="width: 350px">
{| class="wikitable" style="border-left:solid 4px navy;border-right:solid 4px navy;border-top:solid 4px navy;border-bottom:solid 4px navy; font-size:90%; color:navy; align:center"
| colspan="1"''|[[P.vivax gametocyte gallery|Click for ''P.vivax'' gametocyte gallery]]''
|}
</div>

----