Recognition of blast cells with monocytic differentiation - Revision history

John at 17:14, 2 February 2024

2024-02-02T17:14:41Z

← Older revision		Revision as of 19:14, 2 February 2024
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	[[Image:AMLM5B.jpg\|130px\|caption]]<span style="font-size:90%;"> '''B''' monocytic AML</span>		[[Image:AMLM5B.jpg\|130px\|caption]]<span style="font-size:90%;"> '''B''' monocytic AML</span>

	<span style="font-size:90%">'''Panel A''': Where cells have a monoblastic differentiation (generally large blast cells with primitive chromatin and nucleoli that lack ''monocytic shape'' often with basophilic cytoplasm) the monoblasts tend to express markers of primitive phenotype, while typical antigens of monocytic differentiation may be variable or weakly expressed.'''Panel B''': Where cells undergo more appreciable monocytic differentiation (note the more condensed chromatin, lack of nucleolus, and ''monocytic shape'' of there nucleus) these cells tend to have stronger CD45 expression and often express typical monocyte antigens, primitive markers may be variably expressed or absent. *Mixed patterns of monoblastic monocytic and myeloid differentiation within the same case are also frequently found. </br>:''Correlation of immunophenotype with morphology and clinical features may be necessary to accurately identify such cells as blasts.''		<span style="font-size:90%">'''Panel A''': Where cells have a monoblastic differentiation (generally large blast cells with primitive chromatin and nucleoli that lack ''monocytic shape'' often with basophilic cytoplasm) the monoblasts tend to express markers of primitive phenotype, while typical antigens of monocytic differentiation may be variable or weakly expressed.'''Panel B''': Where cells undergo more appreciable monocytic differentiation (note the more condensed chromatin, lack of nucleolus, and ''monocytic shape'' of there nucleus) these cells tend to have stronger CD45 expression and often express typical monocyte antigens, primitive markers may be variably expressed or absent.</br></br>*Mixed patterns of monoblastic monocytic and myeloid differentiation within the same case are also frequently found. </br>''Correlation of immunophenotype with morphology and clinical features may be necessary to accurately identify such cells as blasts.''
	</span>		</span>

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John at 17:13, 2 February 2024

2024-02-02T17:13:47Z

← Older revision		Revision as of 19:13, 2 February 2024
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	[[Image:AMLM5B.jpg\|130px\|caption]]<span style="font-size:90%;"> '''B''' monocytic AML</span>		[[Image:AMLM5B.jpg\|130px\|caption]]<span style="font-size:90%;"> '''B''' monocytic AML</span>

	<span style="font-size:90%">'''Panel A''': Where cells have a monoblastic differentiation (generally large blast cells with primitive chromatin and nucleoli that lack ''monocytic shape'' often with basophilic cytoplasm) the monoblasts tend to express markers of primitive phenotype, while typical antigens of monocytic differentiation may be variable or weakly expressed.'''Panel B''': Where cells undergo more appreciable monocytic differentiation (note the more condensed chromatin, lack of nucleolus, and ''monocytic shape'' of there nucleus) these cells tend to have stronger CD45 expression and often express typical monocyte antigens, primitive markers may be variably expressed or absent. *Mixed patterns of monoblastic monocytic and myeloid differentiation within the same case are also frequently found. </br>:''Correlation of immunophenotype with morphology and clinical features may be necessary to accurately identify such cells as blasts.''		<span style="font-size:90%">'''Panel A''': Where cells have a monoblastic differentiation (generally large blast cells with primitive chromatin and nucleoli that lack ''monocytic shape'' often with basophilic cytoplasm) the monoblasts tend to express markers of primitive phenotype, while typical antigens of monocytic differentiation may be variable or weakly expressed.'''Panel B''': Where cells undergo more appreciable monocytic differentiation (note the more condensed chromatin, lack of nucleolus, and ''monocytic shape'' of there nucleus) these cells tend to have stronger CD45 expression and often express typical monocyte antigens, primitive markers may be variably expressed or absent. *Mixed patterns of monoblastic monocytic and myeloid differentiation within the same case are also frequently found. </br>:''Correlation of immunophenotype with morphology and clinical features may be necessary to accurately identify such cells as blasts.''
	</span>		</span>

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John at 17:13, 2 February 2024

2024-02-02T17:13:23Z

← Older revision		Revision as of 19:13, 2 February 2024
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	[[Image:AMLM5B.jpg\|130px\|caption]]<span style="font-size:90%;"> '''B''' monocytic AML</span>		[[Image:AMLM5B.jpg\|130px\|caption]]<span style="font-size:90%;"> '''B''' monocytic AML</span>

	<~~div~~ style="font-size:90%">		<span style="font-size:90%">'''Panel A''': Where cells have a monoblastic differentiation (generally large blast cells with primitive chromatin and nucleoli that lack ''monocytic shape'' often with basophilic cytoplasm) the monoblasts tend to express markers of primitive phenotype, while typical antigens of monocytic differentiation may be variable or weakly expressed.'''Panel B''': Where cells undergo more appreciable monocytic differentiation (note the more condensed chromatin, lack of nucleolus, and ''monocytic shape'' of there nucleus) these cells tend to have stronger CD45 expression and often express typical monocyte antigens, primitive markers may be variably expressed or absent. *Mixed patterns of monoblastic monocytic and myeloid differentiation within the same case are also frequently found. </br>:''Correlation of immunophenotype with morphology and clinical features may be necessary to accurately identify such cells as blasts.''
	*'''Panel A''': Where cells have a monoblastic differentiation (generally large blast cells with primitive chromatin and nucleoli that lack ''monocytic shape'' often with basophilic cytoplasm) the monoblasts tend to express markers of primitive phenotype, while typical antigens of monocytic differentiation may be variable or weakly expressed.
	*'''Panel B''': Where cells undergo more appreciable monocytic differentiation (note the more condensed chromatin, lack of nucleolus, and ''monocytic shape'' of there nucleus) these cells tend to have stronger CD45 expression and often express typical monocyte antigens, primitive markers may be variably expressed or absent.
	*Mixed patterns of monoblastic monocytic and myeloid differentiation within the same case are also frequently found.

	:''Correlation of immunophenotype with morphology and clinical features may be necessary to accurately identify such cells as blasts.''
	</span>		</span>

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John at 17:12, 2 February 2024

2024-02-02T17:12:25Z

← Older revision		Revision as of 19:12, 2 February 2024
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	[[Image:AMLM5B.jpg\|130px\|caption]]<span style="font-size:90%;"> '''B''' monocytic AML</span>		[[Image:AMLM5B.jpg\|130px\|caption]]<span style="font-size:90%;"> '''B''' monocytic AML</span>

	<~~span~~ style="font-size:90%">		<div style="font-size:90%">
	*'''Panel A''': Where cells have a monoblastic differentiation (generally large blast cells with primitive chromatin and nucleoli that lack ''monocytic shape'' often with basophilic cytoplasm) the monoblasts tend to express markers of primitive phenotype, while typical antigens of monocytic differentiation may be variable or weakly expressed.		*'''Panel A''': Where cells have a monoblastic differentiation (generally large blast cells with primitive chromatin and nucleoli that lack ''monocytic shape'' often with basophilic cytoplasm) the monoblasts tend to express markers of primitive phenotype, while typical antigens of monocytic differentiation may be variable or weakly expressed.
	*'''Panel B''': Where cells undergo more appreciable monocytic differentiation (note the more condensed chromatin, lack of nucleolus, and ''monocytic shape'' of there nucleus) these cells tend to have stronger CD45 expression and often express typical monocyte antigens, primitive markers may be variably expressed or absent.		*'''Panel B''': Where cells undergo more appreciable monocytic differentiation (note the more condensed chromatin, lack of nucleolus, and ''monocytic shape'' of there nucleus) these cells tend to have stronger CD45 expression and often express typical monocyte antigens, primitive markers may be variably expressed or absent.

John at 17:11, 2 February 2024

2024-02-02T17:11:48Z

← Older revision		Revision as of 19:11, 2 February 2024
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	<div id="AML_MonoPic"><span style="font-size:90%;">'''Recognition of blast cells with monocytic differentiation'''</span></div>		<div id="AML_MonoPic"><span style="font-size:90%;">'''Recognition of blast cells with monocytic differentiation'''</span></div>

	[[Image:AMLM5A.jpg\|130px\|caption]] '''A''' monoblastic AML		[[Image:AMLM5A.jpg\|130px\|caption]]<span style="font-size:90%;"> '''A''' monoblastic AML</span>
	[[Image:AMLM5B.jpg\|130px\|caption]] '''B''' monocytic AML		[[Image:AMLM5B.jpg\|130px\|caption]]<span style="font-size:90%;"> '''B''' monocytic AML</span>

	<span style="font-size:90%">		<span style="font-size:90%">

John at 17:10, 2 February 2024

2024-02-02T17:10:42Z

← Older revision		Revision as of 19:10, 2 February 2024
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	<div id="AML_MonoPic">'''Recognition of blast cells with monocytic differentiation'''</div>		<div id="AML_MonoPic"><span style="font-size:90%;">'''Recognition of blast cells with monocytic differentiation'''</span></div>

	[[Image:AMLM5A.jpg\|130px\|caption]] '''A''' monoblastic AML		[[Image:AMLM5A.jpg\|130px\|caption]] '''A''' monoblastic AML

John at 22:12, 11 January 2024

2024-01-11T22:12:15Z

← Older revision		Revision as of 00:12, 12 January 2024
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	<div id="AML_MonoPic">'''Recognition of blast cells with monocytic differentiation'''</div>		<div id="AML_MonoPic">'''Recognition of blast cells with monocytic differentiation'''</div>

John at 22:11, 11 January 2024

2024-01-11T22:11:56Z

← Older revision		Revision as of 00:11, 12 January 2024
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	<div style="width: 200px">		<div style="width: 200px">
	{\| class="wikitable" style="border-left:solid 5px green;border-right:solid 5px green;border-top:solid 5px black;border-bottom:solid 5px black; font-size:90%; color:navy"		{\| class="wikitable" style="border-left:solid 5px green;border-right:solid 5px green;border-top:solid 5px black;border-bottom:solid 5px black; font-size:90%; color:navy"
	\| colspan="1"''\|[[~~The flow cytometric diagnosis~~ of ~~AML~~\|Return to previous page]]''		\| colspan="1"''\|[[Atypical patterns of primitive marker expression in acute myeloid leukaemia\|Return to previous page]]''
	\|}		\|}
	</div>		</div>

John at 22:11, 11 January 2024

2024-01-11T22:11:19Z

← Older revision		Revision as of 00:11, 12 January 2024
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			<div style="width: 200px">
			{\| class="wikitable" style="border-left:solid 5px green;border-right:solid 5px green;border-top:solid 5px black;border-bottom:solid 5px black; font-size:90%; color:navy"
			\| colspan="1"''\|[[The flow cytometric diagnosis of AML\|Return to previous page]]''
			\|}
			</div>

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John: Created page with "----
'''Recognition of blast cells with monocytic differentiation'''
caption '''A''' monoblastic AML caption '''B''' monocytic AML *'''Panel A''': Where cells have a monoblastic differentiation (generally large blast cells with primitive chromatin and nucleoli that lack ''monocytic shape'' often with basophilic cytoplasm) the monoblasts tend to express marke..."

2024-01-11T22:10:29Z

Created page with "---- <div id="AML_MonoPic">'''Recognition of blast cells with monocytic differentiation'''</div> 130px|caption '''A''' monoblastic AML 130px|caption '''B''' monocytic AML <span style="font-size:90%"> *'''Panel A''': Where cells have a monoblastic differentiation (generally large blast cells with primitive chromatin and nucleoli that lack ''monocytic shape'' often with basophilic cytoplasm) the monoblasts tend to express marke..."

New page

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<div id="AML_MonoPic">'''Recognition of blast cells with monocytic differentiation'''</div>

[[Image:AMLM5A.jpg|130px|caption]] '''A''' monoblastic AML
[[Image:AMLM5B.jpg|130px|caption]] '''B''' monocytic AML

<span style="font-size:90%">
*'''Panel A''': Where cells have a monoblastic differentiation (generally large blast cells with primitive chromatin and nucleoli that lack ''monocytic shape'' often with basophilic cytoplasm) the monoblasts tend to express markers of primitive phenotype, while typical antigens of monocytic differentiation may be variable or weakly expressed.
*'''Panel B''': Where cells undergo more appreciable monocytic differentiation (note the more condensed chromatin, lack of nucleolus, and ''monocytic shape'' of there nucleus) these cells tend to have stronger CD45 expression and often express typical monocyte antigens, primitive markers may be variably expressed or absent.
*Mixed patterns of monoblastic monocytic and myeloid differentiation within the same case are also frequently found.

:''Correlation of immunophenotype with morphology and clinical features may be necessary to accurately identify such cells as blasts.''
</span>

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